Small Molecules acting on Myofilaments as Treatments for Heart and Skeletal Muscle Diseases

Small Molecules acting on Myofilaments as Treatments for Heart and Skeletal Muscle Diseases

Hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) are probably the most prevalent types of the continual and progressive pathological situation often called cardiomyopathy. These illnesses have totally different aetiologies; nonetheless, they share the characteristic of haemodynamic abnormalities, which is principally attributable to dysfunction within the contractile proteins that make up the contractile unit often called the sarcomere. Up to now, pharmacological remedy choices usually are not disease-specific and reasonably deal with managing the signs, with out addressing the illness mechanism. Earliest makes an attempt at bettering cardiac contractility by modulating the sarcomere not directly (inotropes) resulted in negative effects. In distinction, concentrating on the sarcomere instantly, aided by high-throughput screening techniques, may establish small molecules with a superior therapeutic worth in cardiac muscle problems.

Herein, an in depth literature assessment of 21 small molecules directed to 5 totally different targets was carried out. A easy scoring system was created to evaluate the suitability of small molecules for remedy by evaluating them in eight totally different standards. A lot of the compounds failed attributable to lack of goal specificity or poor physicochemical properties. Six compounds stood out, exhibiting a possible therapeutic worth in HCM, DCM or coronary heart failure (HF). Omecamtiv Mecarbil and Danicamtiv (myosin activators), Mavacamten, CK-274 and MYK-581 (myosin inhibitors) and AMG 594 (Ca2+-sensitiser) are all small molecules that allosterically modulate troponin or myosin.

 

Omecamtiv Mecarbil confirmed restricted efficacy in part III GALACTIC-HF trial, whereas, outcomes from part III EXPLORER-HCM trial had been lately printed, indicating that Mavacamten diminished left ventricular outflow tract (LVOT) obstruction and diastolic dysfunction and improved the well being standing of sufferers with HCM. A novel class of small molecules often called “recouplers” was reported to focus on a phenomenon termed uncoupling generally present in familial cardiomyopathies however has not progressed past preclinical work. In conclusion, the contractile equipment is a promising goal for brand spanking new drug improvement.

 

VIPERdb v3.0: a structure-based information analytics platform for viral capsids

VIrus Particle ExploreR information base (VIPERdb) (http://viperdb.scripps.edu) is a curated repository of virus capsid buildings and a database of structure-derived information together with numerous virus particular info. VIPERdb has been constantly improved for over 20 years and comprises quite a few virus construction evaluation instruments. The discharge of VIPERdb v3.Zero comprises new structure-based information analytics instruments like A number of Construction-based and Sequence Alignment (MSSA) to establish hot-spot residues inside a particular group of buildings and an anomaly detection utility to research and curate the structure-derived information inside particular person virus households.
On the time of this writing, there are 931 virus buildings from 62 totally different virus households within the database. Considerably, the brand new launch additionally comprises a standalone database known as ‘Virus World database’ (VWdb) that contains all of the characterised viruses (∼181 000) identified up to now, gathered from ICTVdb and NCBI, and their capsid protein sequences, organized in line with their virus taxonomy with hyperlinks to identified buildings in VIPERdb and PDB. Furthermore, the brand new launch of VIPERdb features a service-oriented information engine to deal with all the info entry requests and gives an interface for futuristic information analytics utilizing machine leaning functions.
Publish-transcriptional regulation by way of RNA-binding proteins performs a basic position in each organism, however the regulatory mechanisms lack vital understanding. Nonetheless, they are often elucidated by cross-linking immunoprecipitation together with high-throughput sequencing (CLIP-Seq). CLIP-Seq solutions questions in regards to the useful position of an RNA-binding protein and its targets by figuring out binding websites on a nucleotide degree and related sequence and structural binding patterns. In recent times the quantity of CLIP-Seq information skyrocketed, urging the necessity for an computerized information evaluation that may take care of totally different experimental set-ups. Nevertheless, noncanonical information, new protocols, and an enormous number of instruments, particularly for peak calling, made it tough to outline a normal.
Small Molecules acting on Myofilaments as Treatments for Heart and Skeletal Muscle Diseases

Round RNA Sequencing of Maternal Platelets: A Novel Software for the Identification of Being pregnant-Particular Biomarkers

Within the first trimester of being pregnant, the maternal platelet is instantly concerned in a optimistic suggestions mechanism that facilitates invasion of the extravillous trophoblast into the maternal spiral arteries. Dysfunctional trophoblast invasion with faulty deep placentation is primordial within the etiology of the “nice obstetrical syndromes.”
On this proof-of-concept research, utilizing transcriptome evaluation of round RNA (circRNA) following RNA sequencing of maternal platelets, we examined whether or not pregnancy-specific circRNA markers might be recognized within the first trimester of regular pregnancies. Differential transcript expression evaluation of circRNAs, as predicted by Correct CircRNA Finder Suite, CircRNA Identifier (model 2), and Identified and Novel Isoform Explorer, was finished utilizing thromboSeq.R with variation of a number of settings. Take a look at efficiency was checked for (a) de novo circRNA identification utilizing the novel platelet-specific Plt-circR4 as a optimistic management, (b) full segregation of teams (pregnant vs nonpregnant) after warmth map-dendrogram clustering, (c) identification of pregnancy-specific circRNA markers at a false discovery charge (FDR) <0.05, and (d) affirmation of differentially expressed circRNA markers with an FDR <0.05 by an impartial methodology, reverse transcription-quantitative PCR.

Rabbit Heat Shock Protein 90,HSP-90 ELISA Kit

GA-E0090RB-96T 96T
EUR 628.8

Rabbit Heat Shock Protein 90,HSP-90 ELISA Kit

QY-E30209 96T
EUR 448.8

Rabbit Heat Shock Protein 90,HSP-90 ELISA Kit

SL0089Rb -
EUR 498

Rabbit Heat shock protein HSP 90- alpha, HSP90AA1 ELISA KIT

ELI-02919Ra 96 Tests
EUR 1113.6

Mouse Heat shock protein HSP 90- beta, Hsp90ab1 ELISA KIT

ELI-31341m 96 Tests
EUR 1038

Human Heat shock protein HSP 90- beta, HSP90AB1 ELISA KIT

ELI-48675h 96 Tests
EUR 988.8

Bovine Heat shock protein HSP 90- beta, HSP90AB1 ELISA KIT

ELI-07968b 96 Tests
EUR 1113.6

Rat Heat shock protein HSP 90-beta(HSP90AB1) ELISA kit

CSB-EL010808RA-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rat Heat shock protein HSP 90-beta (HSP90AB1) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Heat shock protein HSP 90-beta(HSP90AB1) ELISA kit

1-CSB-EL010808RA
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  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Heat shock protein HSP 90-beta(HSP90AB1) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Heat Shock Protein HSP 90-Beta (HSP90AB1) ELISA Kit

abx155648-100g 100 µg
EUR 687.5

Rat Heat Shock Protein HSP 90-Beta (HSP90AB1) ELISA Kit

abx155648-1mg 1 mg
EUR 6187.5

Rat Heat Shock Protein HSP 90-Beta (HSP90AB1) ELISA Kit

abx155648-200g 200 µg
EUR 3275

Mouse Heat shock protein HSP 90-beta(HSP90AB1) Elisa kit

EK731012 96 Wells
EUR 0.74

Mouse Heat shock protein HSP 90-beta(HSP90AB1) ELISA kit

EKC37028-48T 48T
EUR 535.99

Mouse Heat shock protein HSP 90-beta(HSP90AB1) ELISA kit

EKC37028-5x96T 5x96T
EUR 3637.08

Mouse Heat shock protein HSP 90-beta(HSP90AB1) ELISA kit

EKC37028-96T 96T
EUR 765.7

Human Heat shock protein HSP 90-beta(HSP90AB1) ELISA kit

EKC41633-48T 48T
EUR 535.99

Human Heat shock protein HSP 90-beta(HSP90AB1) ELISA kit

EKC41633-5x96T 5x96T
EUR 3637.08

Human Heat shock protein HSP 90-beta(HSP90AB1) ELISA kit

EKC41633-96T 96T
EUR 765.7

Human Heat shock protein HSP 90-beta(HSP90AB1) Elisa Kit

EK712683 96 Wells
EUR 0.28

Human Heat shock protein HSP 90-beta(HSP90AB1) ELISA kit

CSB-EL010808HU-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Heat shock protein HSP 90-beta (HSP90AB1) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Heat shock protein HSP 90-beta(HSP90AB1) ELISA kit

1-CSB-EL010808HU
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Description: Quantitativesandwich ELISA kit for measuring Human Heat shock protein HSP 90-beta(HSP90AB1) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Heat shock protein HSP 90-beta(HSP90AB1) ELISA kit

CSB-EL010808MO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse Heat shock protein HSP 90-beta (HSP90AB1) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Heat shock protein HSP 90-beta(HSP90AB1) ELISA kit

1-CSB-EL010808MO
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Description: Quantitativesandwich ELISA kit for measuring Mouse Heat shock protein HSP 90-beta(HSP90AB1) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Heat shock protein HSP 90-beta (HSP90AB1) ELISA Kit

RK13082 96T
EUR 280

Rabbit Heat Shock Protein 90 (HSP90) ELISA Kit

abx362603-96tests 96 tests
EUR 904.8

Rabbit Heat Shock Protein 70 HSP-70 ELISA Kit

E01A31302 96T
EUR 700
Description: ELISA

Rabbit Heat Shock Protein 70 HSP-70 ELISA kit

E04H0301-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rabbit Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Heat Shock Protein 70 HSP-70 ELISA kit

E04H0301-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rabbit Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Heat Shock Protein 70 HSP-70 ELISA kit

E04H0301-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rabbit Heat Shock Protein 70 HSP-70 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Heat Shock Protein 40 (HSP-40) ELISA Kit

AE39296RB-48Tests 48 Tests
EUR 360
Description: Rabbit (Oryctolagus cuniculus)

Rabbit Heat Shock Protein 40 (HSP-40) ELISA Kit

AE39296RB-96Tests 96 Tests
EUR 680
Description: Rabbit (Oryctolagus cuniculus)

Rabbit Heat Shock Protein 70,HSP-70 ELISA Kit

CN-00635R1 96T
EUR 553.2

Rabbit Heat Shock Protein 70,HSP-70 ELISA Kit

CN-00635R2 48T
EUR 372

Rabbit Heat Shock Protein 40,HSP-40 ELISA Kit

CN-00636R1 96T
EUR 553.2

Rabbit Heat Shock Protein 40,HSP-40 ELISA Kit

CN-00636R2 48T
EUR 372

Rabbit Heat Shock Protein 20,HSP-20 ELISA Kit

CN-00637R1 96T
EUR 553.2

Rabbit Heat Shock Protein 20,HSP-20 ELISA Kit

CN-00637R2 48T
EUR 372

Rabbit Heat Shock Protein 20,HSP-20 ELISA Kit

GA-E0087RB-48T 48T
EUR 391.2

Rabbit Heat Shock Protein 20,HSP-20 ELISA Kit

GA-E0087RB-96T 96T
EUR 628.8

Rabbit Heat Shock Protein 40,HSP-40 ELISA Kit

GA-E0088RB-48T 48T
EUR 391.2

Rabbit Heat Shock Protein 40,HSP-40 ELISA Kit

GA-E0088RB-96T 96T
EUR 628.8

Rabbit Heat Shock Protein 70,HSP-70 ELISA Kit

GA-E0089RB-48T 48T
EUR 391.2

Rabbit Heat Shock Protein 70,HSP-70 ELISA Kit

GA-E0089RB-96T 96T
EUR 628.8

Rabbit Heat Shock Protein 70,HSP-70 ELISA Kit

QY-E30210 96T
EUR 448.8

Rabbit Heat Shock Protein 40,HSP-40 ELISA Kit

QY-E30211 96T
EUR 448.8

Rabbit Heat Shock Protein 20,HSP-20 ELISA Kit

QY-E30212 96T
EUR 448.8

Rabbit Heat Shock Protein 20,HSP-20 ELISA Kit

SL0086Rb -
EUR 498

Rabbit Heat Shock Protein 40,HSP-40 ELISA Kit

SL0087Rb -
EUR 498

Rabbit Heat Shock Protein 70,HSP-70 ELISA Kit

SL0088Rb -
EUR 498

Rat heat shock protein 90(HSP-90) Elisa Kit

EK720499 96 Wells
EUR 0.57

Rat heat shock protein 90,hSP-90 ELISA Kit

CN-01862R1 96T
EUR 538.8

Rat heat shock protein 90(hSP-90)ELISA Kit

GA-E0531RT-48T 48T
EUR 380.4

Rat heat shock protein 90(hSP-90)ELISA Kit

GA-E0531RT-96T 96T
EUR 595.2

Rat Heat shock protein 90(Hsp-90) ELISA Kit

NSL0480r 96 Tests
EUR 498

Rat heat shock protein 90(hSP-90)ELISA Kit

QY-E11121 96T
EUR 480

Rat heat shock protein 90,hSP-90 ELISA Kit

SL0337Ra -
EUR 498

Rat heat shock protein 90,hSP-90 ELISA Kit

YLA0448RA-48T 48T Ask for price

Rat heat shock protein 90,hSP-90 ELISA Kit

YLA0448RA-96T 96T Ask for price

Fish Heat Shock Protein 90 (HSP-90) ELISA Kit

EK10355 96Т
EUR 799

Fish Heat Shock Protein 90 (HSP-90) ELISA Kit

AE39284FI-48Tests 48 Tests
EUR 360
Description: Fish

Fish Heat Shock Protein 90 (HSP-90) ELISA Kit

AE39284FI-96Tests 96 Tests
EUR 680
Description: Fish

Goat Heat shock protein 90(Hsp-90) ELISA Kit

NSL0604Gt 96T
EUR 528

Goat Heat Shock Protein 90 (HSP-90) ELISA Kit

QY-E140075 96T
EUR 495.6

Goat Heat Shock Protein 90 (HSP-90)ELISA Kit

SL0052Gt - Ask for price

Fish Heat Shock Protein 90(HSP-90)ELISA Kit

YLA0070FI-48T 48T Ask for price

Fish Heat Shock Protein 90(HSP-90)ELISA Kit

YLA0070FI-96T 96T Ask for price

Goat Heat Shock Protein 90,HSP-90 ELISA Kit

YLA0098GO-48T 48T Ask for price

Goat Heat Shock Protein 90,HSP-90 ELISA Kit

YLA0098GO-96T 96T Ask for price

Rat Heat shock Protein HSP 90-beta, HSP90AB1 GENLISA ELISA

KLR2005 1 x 96 wells
EUR 341

Human Heat Shock Protein 90,HSP-90 ELISA Kit

201-12-1805 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Mouse Heat Shock Protein 90,Hsp-90 Elisa Kit

EK730173 96 Wells
EUR 0.66

Mouse Heat Shock Protein 90,Hsp-90 ELISA Kit

EKC37025-48T 48T
EUR 631.26

Mouse Heat Shock Protein 90,Hsp-90 ELISA Kit

EKC37025-5x96T 5x96T
EUR 4283.55

Mouse Heat Shock Protein 90,Hsp-90 ELISA Kit

EKC37025-96T 96T
EUR 901.8

Human Heat Shock Protein 90(HSP-90) Elisa Kit

EK711021 96 Wells
EUR 0.13

Mouse Heat Shock Protein 90, Hsp-90 ELISA Kit

CSB-E08312m-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse Heat Shock Protein 90, Hsp-90 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Heat Shock Protein 90, Hsp-90 ELISA Kit

1-CSB-E08312m
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Description: Quantitativesandwich ELISA kit for measuring Mouse Heat Shock Protein 90, Hsp-90 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Heat Shock Protein 90,HSP-90 ELISA Kit

CN-03553H1 96T
EUR 567.6

Human Heat Shock Protein 90,HSP-90 ELISA Kit

CN-03553H2 48T
EUR 387.6

Mouse Heat Shock Protein 90,Hsp-90 ELISA Kit

CN-02740M1 96T
EUR 548.4

Mouse Heat Shock Protein 90,Hsp-90 ELISA Kit

CN-02740M2 48T
EUR 367.2

Human Heat Shock Protein 90(HSP-90)ELISA Kit

GA-E1821HM-48T 48T
EUR 346.8

Human Heat Shock Protein 90(HSP-90)ELISA Kit

GA-E1821HM-96T 96T
EUR 559.2

Mouse Heat Shock Protein 90(Hsp-90)ELISA Kit

GA-E0314MS-48T 48T
EUR 403.2

Mouse Heat Shock Protein 90(Hsp-90)ELISA Kit

GA-E0314MS-96T 96T
EUR 640.8

Human heat shock protein 90(Hsp-90)ELISA Kit

NSL1984Hu 96 wells
EUR 468

Mouse heat shock protein 90(hSP-90)ELISA Kit

QY-E20717 96T
EUR 433.2

Mouse Heat Shock Protein 90 (HSP-90) ELISA Kit

RK07369 96T
EUR 280

Human Heat Shock Protein 90(HSP-90)ELISA Kit

QY-E01784 96T
EUR 433.2

Mouse Heat Shock Protein 90,Hsp-90 ELISA Kit

SL0257Mo -
EUR 528

Human Heat Shock Protein 90,HSP-90 ELISA Kit

SL0832Hu 96 Tests
EUR 468

Horse Heat Shock Protein 90 (HSP-90) ELISA Kit

SL0051Ho -
EUR 528

Human Heat Shock Protein 90,HSP-90 ELISA Kit

YLA1855HU-48T 48T Ask for price

Human Heat Shock Protein 90,HSP-90 ELISA Kit

YLA1855HU-96T 96T Ask for price

Mouse Heat Shock Protein 90,Hsp-90 ELISA Kit

YLA0762MO-48T 48T Ask for price

Mouse Heat Shock Protein 90,Hsp-90 ELISA Kit

YLA0762MO-96T 96T Ask for price

Rat HSP-90 (Heat Shock Protein 90) ELISA Kit

EKE62140-5x96T 5x96T
EUR 2667.6

Rat HSP-90 (Heat Shock Protein 90) ELISA Kit

EKE62140-96T 96T
EUR 561.6

Rat HSP-90(Heat Shock Protein 90) ELISA Kit

ER1058 96T
EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 75pg/ml

Rat HSP-90(Heat Shock Protein 90) ELISA Kit

RE2084R-48wells 48 wells
EUR 125.55

Rat HSP-90(Heat Shock Protein 90) ELISA Kit

RE2084R-96wells 96 wells
EUR 179.55

Rabbit Heat Shock Protein Beta-1 (HSPB1) ELISA Kit

abx362180-100g 100 µg
EUR 675

Bovine Heat shock protein 90(Hsp-90) ELISA Kit

NSL0398Bo 96 T
EUR 528

Canine Heat shock protein 90(Hsp-90) ELISA Kit

NSL0474Ca 569 wells
EUR 528

Bovine Heat Shock Protein 90 (HSP-90)ELISA Kit

SL0212Bo - Ask for price

Bovine Heat Shock Protein 90,HSP-90 ELISA Kit

YLA0296BO-48T 48T Ask for price

Bovine Heat Shock Protein 90,HSP-90 ELISA Kit

YLA0296BO-96T 96T Ask for price

Mouse Heat shock Protein HSP 90-beta, HSP90AB1 GENLISA ELISA

KLM2124 1 x 96 wells
EUR 341

Human Heat shock Protein HSP 90-beta, HSP90AB1 GENLISA ELISA

KBH5382 1 x 96 wells
EUR 286

Rabbit Heat Shock Protein 20 HSP 20 ELISA kit

E01A31297 96T
EUR 700
Description: ELISA

Rabbit Heat Shock Protein 20 HSP 20 ELISA kit

E04H0285-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rabbit Heat Shock Protein 20 HSP 20 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Heat Shock Protein 20 HSP 20 ELISA kit

E04H0285-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rabbit Heat Shock Protein 20 HSP 20 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Heat Shock Protein 20 HSP 20 ELISA kit

E04H0285-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rabbit Heat Shock Protein 20 HSP 20 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Porcine Heat Shock Protein 90,HSP-90 Elisa Kit

EK751036 96 Wells
EUR 0.87

Chicken Heat Shock Protein 90(HSP-90) Elisa Kit

EK780038 96 Wells
EUR 0.98

Chicken Heat Shock Protein 90,HSP-90 ELISA Kit

EKC31937-48T 48T
EUR 597.24

Chicken Heat Shock Protein 90,HSP-90 ELISA Kit

EKC31937-5x96T 5x96T
EUR 4052.7

Chicken Heat Shock Protein 90,HSP-90 ELISA Kit

EKC31937-96T 96T
EUR 853.2

Chicken Heat Shock Protein 90, HSP-90 ELISA Kit

CSB-E12873C-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Chicken Heat Shock Protein 90, HSP-90 in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Chicken Heat Shock Protein 90, HSP-90 ELISA Kit

1-CSB-E12873C
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  • 1 plate of 96 wells
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Description: Quantitativesandwich ELISA kit for measuring Chicken Heat Shock Protein 90, HSP-90 in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

PoFAine Heat Shock Protein 90,HSP-90 ELISA Kit

CN-01297P1 96T
EUR 548.4

PoFAine Heat Shock Protein 90,HSP-90 ELISA Kit

CN-01297P2 48T
EUR 367.2

Porcine heat shock protein 90(Hsp-90)ELISA Kit

NSL1112Po 96T
EUR 528

Chicken Heat shock protein 90(Hsp-90) ELISA Kit

NSL0658Ch 753 T
EUR 528

Porcine heat shock protein 90 (HSP-90) ELISA Kit

QY-E40083 96T
EUR 480

Porcine Heat Shock Protein 90,HSP-90 ELISA Kit

SL0053Po -
EUR 528

Chicken Heat Shock Protein 90 (HSP-90) ELISA Kit

SL0200Ch - Ask for price

Porcine Heat Shock Protein 90,HSP-90 ELISA Kit

YLA0295PO-48T 48T Ask for price

Porcine Heat Shock Protein 90,HSP-90 ELISA Kit

YLA0295PO-96T 96T Ask for price

Mouse HSP-90 (Heat Shock Protein 90) ELISA Kit

EKE61665-5x96T 5x96T
EUR 2667.6

Mouse HSP-90 (Heat Shock Protein 90) ELISA Kit

EKE61665-96T 96T
EUR 561.6

Human HSP-90 (Heat Shock Protein 90) ELISA Kit

EKE61082-5x96T 5x96T
EUR 2667.6

Human HSP-90 (Heat Shock Protein 90) ELISA Kit

EKE61082-96T 96T
EUR 561.6

Mouse HSP-90(Heat Shock Protein 90) ELISA Kit

EM1138 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

Human HSP-90(Heat Shock Protein 90) ELISA Kit

RE2084H-48wells 48 wells
EUR 125.55

Human HSP-90(Heat Shock Protein 90) ELISA Kit

RE2084H-96wells 96 wells
EUR 179.55

Rabbit Heat Shock Protein Beta 2(HSPb2)ELISA Kit

QY-E30038 96T
EUR 448.8

Human Putative heat shock protein HSP 90-beta-3 (HSP90AB3P) ELISA Kit

abx526703-96tests 96 tests
EUR 687.5

Human Heat shock protein HSP 90-beta (HSP90AB1)

1-CSB-EP010808HU
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Description: Recombinant Human Heat shock protein HSP 90-beta(HSP90AB1) expressed in E.coli

Heat Shock Protein HSP 90-Beta (HSP90B) Antibody

20-abx012748
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  • 100 ug
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Heat Shock Protein HSP 90-Beta (HSP90B) Antibody

abx012748-100g 100 µg
EUR 237.5

Heat Shock Protein HSP 90-Beta (HSP90B) Antibody

abx012748-10g 10 µg
EUR 43.75

Heat Shock Protein HSP 90-Beta (HSP90B) Antibody

abx012748-200g 200 µg
EUR 312.5

Rabbit Heat Shock Protein Beta-6 / HSP20 (HSPB6) ELISA Kit

abx362943-96tests 96 tests
EUR 904.8

Human Putative heat shock protein HSP 90-beta 2 (HSP90AB2P) ELISA Kit

abx526702-96tests 96 tests
EUR 687.5

Human Putative heat shock protein HSP 90-beta 4 (HSP90AB4P) ELISA Kit

abx526704-96tests 96 tests
EUR 687.5

Heat Shock Protein HSP 90-Beta (HSP90AB1) Antibody

20-abx133116
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Heat Shock Protein HSP 90-Beta (HSP90AB1) Antibody

20-abx134351
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  • 100 ul
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  • 30 ul

Heat Shock Protein HSP 90-Beta (HSP90AB1) Antibody

abx139528-01mg 0.1 mg
EUR 577.2

Heat Shock Protein HSP 90-Beta (HSP90AB1) Antibody

20-abx444869
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  • 100 ug
  • 25 ug

Heat Shock Protein HSP 90-Beta (HSP90AB1) Antibody

20-abx445143
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  • 100 ul
  • 25 ul

Heat Shock Protein HSP 90-Beta (HSP90AB1) Antibody

abx139528-100l 100 µl
EUR 400

Heat Shock Protein HSP 90-Beta (HSP90AB1) Antibody

abx139528-500l 500 µl Ask for price

Heat shock protein HSP 90-beta (HSP90AB1) Antibody

abx402364-100g 100 µg
EUR 287.5

Heat shock protein HSP 90-beta (HSP90AB1) Antibody

abx402466-500g 500 µg
EUR 287.5

Heat Shock Protein HSP 90-Beta (HSP90AB1) Antibody

abx444869-200l 200 µl
EUR 362.5

Heat Shock Protein HSP 90-Beta (HSP90AB1) Antibody

abx445143-100g 100 µg
EUR 312.5

Rabbit Heat Shock Protein 90 ELISA kit

E01A31303 96T
EUR 700
Description: ELISA

Rabbit Heat Shock Protein 90 ELISA kit

E04H0304-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Heat Shock Protein 90 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Heat Shock Protein 90 ELISA kit

E04H0304-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Heat Shock Protein 90 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Heat Shock Protein 90 ELISA kit

E04H0304-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Heat Shock Protein 90 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Heat Shock Protein 90 ELISA Kit

ELA-E0863Rb 96 Tests
EUR 1113.6

Rabbit Heat Shock Protein 90 Alpha (HSP90A) ELISA Kit

abx362603-100g 100 µg
EUR 600

Rabbit Heat Shock Protein 90kDa Beta 1(HSP90b1)ELISA Kit

QY-E30039 96T
EUR 448.8

Rabbit Heat Shock Protein 90kDa Beta 1 (HSP90b1)ELISA kit

YLA0121RB-48T 48T Ask for price

Rabbit Heat Shock Protein 90kDa Beta 1 (HSP90b1)ELISA kit

YLA0121RB-96T 96T Ask for price

HSP-90 ELISA Kit| Rat Heat Shock Protein 90 ELISA Kit

EF017815 96 Tests
EUR 826.8

ELISA kit for Rat HSP-90 (Heat Shock Protein 90)

E-EL-R0480 1 plate of 96 wells
EUR 452.4
Description: A sandwich ELISA kit for quantitative measurement of Rat HSP-90 (Heat Shock Protein 90) in samples from Serum, Plasma, Cell supernatant

HSP-90 ELISA Kit| Mouse Heat Shock Protein 90 ELISA Kit

EF013694 96 Tests
EUR 826.8

Guinea pig Heat shock protein 90(Hsp-90) ELISA Kit

NSL0679Gp 96T
EUR 528

ELISA kit for Mouse HSP-90 (Heat Shock Protein 90)

E-EL-M0620 1 plate of 96 wells
EUR 452.4
Description: A sandwich ELISA kit for quantitative measurement of Mouse HSP-90 (Heat Shock Protein 90) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human HSP-90 (Heat Shock Protein 90)

E-EL-H1864 1 plate of 96 wells
EUR 452.4
Description: A sandwich ELISA kit for quantitative measurement of Human HSP-90 (Heat Shock Protein 90) in samples from Serum, Plasma, Cell supernatant

Rat Heat shock protein HSP 90-alpha( HSP 90-alpha) ELISA Kit

QY-E11796 96T
EUR 448.8

Rat heat shock protein 90,hSP-91 ELISA Kit

CN-01862R2 48T
EUR 358.8
Of the differentially expressed circRNAs with P values <0.05, 41 circRNAs had been upregulated (logFC >2), and 52 circRNAs had been downregulated (logFC lower than -2) in first-trimester platelet RNA. Of those, nuclear receptor-interacting protein 1 circRNA protecting exons 2 and three of the 5′-untranslated area was being pregnant particular with upregulation in first-trimester maternal platelets in comparison with nonpregnant controls.

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