Discovery of novel isoliquiritigenin analogue ISL-17 as a potential anti-gastric cancer agent

Discovery of novel isoliquiritigenin analogue ISL-17 as a potential anti-gastric cancer agent

Isoliquiritigenin (ISL), a pure product remoted from licorice root, displays anti-gastric most cancers results. Nevertheless, purposes of ISL are nonetheless restricted in scientific follow as a result of its poor bioavailability. To discovery of more practical anti-gastric most cancers brokers primarily based on ISL, aldol condensation response was utilized to synthesize the ISL analogues. MTS assay was used to guage the inhibitory actions of ISL analogues towards SGC-7901, BGC-823 and GES-1 cells in vitro. Cell cycle distribution, apoptosis and reactive oxygen species (ROS) era had been detected by move cytometry.

Western blot assay was used to investigate the expression ranges of associated proteins. The drug-likeness and pharmacokinetic properties had been predicted with Osiris property explorer and PreADMET server. In consequence, 18 new ISL analogues (ISL-1 to ISL-18) had been synthesized. Amongst these analogues, ISL-17 confirmed the strongest inhibitory actions towards SGC-7901 and BGC-823 cells, and will induce G2/M cell cycle arrest and apoptosis in these two cell traces. Remedy with ISL-17 resulted in elevated ROS manufacturing and elevated autophagy ranges in SGC-7901 cells.

The PI3K/AKT/mTOR signaling pathway was down-regulated after remedy with ISL-17 in SGC-7901 cells. The outcomes of drug-likeness and pharmacokinetic prediction indicated that every one the ISL analogues complied with Lipinski’s rule of 5 and Veber rule and had a good ADME character. Total, our outcomes attest that ISL-17 holds promise as a candidate agent towards gastric most cancers.

Analyzing the prognostic worth of DKK1 expression in human cancers primarily based on bioinformatics.

The Dickkopf1 (DKK1) gene encodes a protein that belongs to the Dickkopf household. The protein can inhibit the Wnt signaling pathway which performs a key function within the carcinogenesis and development of assorted forms of cancers. Based mostly on this, we hypothesized that the differential expression of DKK1 could determine considerably in cancers by regulating Wnt signaling pathway transduction. On this research, we carried out bioinformatics evaluation to guage the prognostic and therapeutic worth of DKK1 expression degree in human cancers.

The expression degree was analyzed by utilizing the Oncomine database and Gene Expression Profiling Interactive Evaluation device. The evaluation of prognosis was carried out by utilizing the UALCAN, Gene Expression Profiling Interactive Evaluation (GEPIA), and DriverDBv3 databases. We additionally investigated utilizing DKK1 promoter methylation to outline most cancers sorts via the UALCAN database. In the meantime, the associated purposeful networks of DKK1 had been analyzed by utilizing the GeneMANIA interactive device and Cytoscape software program. Moreover, Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway evaluation was carried out utilizing the Metascape on-line web site, and we used the cBioPotartal database to explored DKK1 expression, aberrant data, and the co-expression genes within the subgroups of lung most cancers. Lastly, we carried out the general survival (OS) meta-analysis of the DKK1 expression in lung squamous cell carcinoma (LUSC) by way of the Lung Most cancers Explorer (LCE).DKK1 was differentially expressed in several types of human cancers. DKK1 was overexpressed in human cancers together with head and neck squamous cell carcinoma (HNSC), LUSC, and pancreatic adenocarcinoma (PAAD).

Overexpression of DKK1 indicated adversarial OS in bladder urothelial carcinoma (BLCA), HNSC, and PADD, however no distinction in OS was discovered between the LUSC and wholesome teams. The excessive expression of DKK1 was additionally related to shorter disease-free survival (DFS) in HNSC, LUSC, and PAAD. Gene regulation community evaluation indicated that DKK1 was primarily concerned in Wnt signaling pathways and a number of other different signaling pathways.Our findings confirmed that DKK1 is considerably expressed in varied cancers and may very well be a biomarker for focused remedy and a predictor for prognosis of those particular cancers.
The bioinformatics evaluation revealed a big overexpression of DKK1 in HNSC, LUSC, and PAAD, with DKK1 overexpression being related to adversarial end result in these sufferers, however how DKK1 expression ranges relate to hematological malignancies and prognosis remains to be unclear. These new insights into the perform of DKK1 could present a foundation for brand new focused drug remedy and an avenue for additional investigation into the mechanisms underlying carcinogenesis of DKK1 in several most cancers sorts.Discovery of novel isoliquiritigenin analogue ISL-17 as a potential anti-gastric cancer agent

Genetic and structural research of RABL3 reveal a vital function in lymphoid growth and performance.

The small GTPase RABL3 is an oncogene of unknown physiological perform. Homozygous knockout alleles of mouse Rabl3 had been embryonic deadly, however a viable hypomorphic allele (xiamen [xm]) inflicting in-frame deletion of 4 amino acids from the interswitch area resulted in profound defects in lymphopoiesis. Impaired lymphoid progenitor growth led to deficiencies of B cells, T cells, and pure killer (NK) cells in Rabl3xm/xm mice. T cells and NK cells exhibited impaired cytolytic exercise, and mice contaminated with mouse cytomegalovirus (MCMV) displayed elevated titers within the spleen.
Myeloid cells had been regular in quantity and performance. Biophysical and crystallographic research demonstrated that RABL3 fashioned a homodimer in resolution by way of interactions between the effector binding surfaces on every subunit; monomers adopted a typical small G protein fold. RABL3xm displayed a big compensatory alteration in swap I, which adopted a β-strand configuration usually supplied by the deleted interswitch residues, thereby allowing homodimer formation.

Coiled Coil Domain Containing Protein 60 (CCDC60) Antibody

abx104217-50g 50 µg
EUR 375

Coiled Coil Domain Containing Protein 60 (CCDC60) Antibody

abx104218-100g 100 µg
EUR 900

Coiled Coil Domain Containing Protein 60 (CCDC60) Antibody

abx104218-20g 20 µg
EUR 300

Coiled Coil Domain Containing Protein 60 (CCDC60) Antibody

abx104218-50g 50 µg
EUR 387.5

Coiled Coil Domain Containing Protein 60 (CCDC60) Antibody

abx104219-100g 100 µg
EUR 937.5

Coiled Coil Domain Containing Protein 60 (CCDC60) Antibody

abx104219-20g 20 µg
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Coiled Coil Domain Containing Protein 60 (CCDC60) Antibody

abx104219-50g 50 µg
EUR 400

Coiled Coil Domain Containing Protein 60 (CCDC60) Antibody

abx128379-100l 100 µl
EUR 287.5

Coiled Coil Domain Containing Protein 60 (CCDC60) Antibody

abx128379-1ml 1 ml
EUR 825

Coiled Coil Domain Containing Protein 60 (CCDC60) Antibody

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Coiled Coil Domain Containing Protein 60 (CCDC60) Antibody (Biotin)

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Coiled Coil Domain Containing Protein 60 (CCDC60) Antibody (Biotin)

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Coiled Coil Domain Containing Protein 60 (CCDC60) Antibody (Biotin)

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Coiled Coil Domain Containing Protein 60 (CCDC60) Antibody (Biotin)

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Coiled Coil Domain Containing Protein 60 (CCDC60) Antibody (Biotin)

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Coiled Coil Domain Containing Protein 60 (CCDC60) Monoclonal Antibody

CAU29900-100ul 100ul
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Coiled Coil Domain Containing Protein 60 (CCDC60) Monoclonal Antibody

CAU29900-200ul 200ul
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Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody

CAU21012-100ul 100ul
EUR 281.3
Description: polyclonal

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody

CAU21012-200ul 200ul
EUR 351.1
Description: polyclonal

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody

CAU21013-100ul 100ul
EUR 265.9
Description: polyclonal

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody

CAU21013-200ul 200ul
EUR 332.6
Description: polyclonal

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody

CAU21014-100ul 100ul
EUR 258.2
Description: polyclonal

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody

CAU21014-200ul 200ul
EUR 322.6
Description: polyclonal

Polyclonal Antibody to Coiled Coil Domain Containing Protein 60 (CCDC60)

PAU807Hu01 100ul
EUR 269

Polyclonal Antibody to Coiled Coil Domain Containing Protein 60 (CCDC60)

PAU807Mu01 100ul
EUR 277

Polyclonal Antibody to Coiled Coil Domain Containing Protein 60 (CCDC60)

PAU807Ra01 100ul
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Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Rat)

4-PAU807Ra01
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Description: A Rabbit polyclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60)

Coiled Coil Domain Containing Protein 60 (CCDC60) Monoclonal Antibody (Rat)

4-MAU807Ra21
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Description: A Mouse monoclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60)

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Human)

4-PAU807Hu01
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Description: A Rabbit polyclonal antibody against Human Coiled Coil Domain Containing Protein 60 (CCDC60)

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Mouse)

4-PAU807Mu01
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Description: A Rabbit polyclonal antibody against Mouse Coiled Coil Domain Containing Protein 60 (CCDC60)

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Rat), APC

4-PAU807Ra01-APC
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Description: A Rabbit polyclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with APC.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Rat), Cy3

4-PAU807Ra01-Cy3
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Description: A Rabbit polyclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with Cy3.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Rat), HRP

4-PAU807Ra01-HRP
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Description: A Rabbit polyclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with HRP.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Rat), PE

4-PAU807Ra01-PE
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Description: A Rabbit polyclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with PE.

Coiled Coil Domain Containing Protein 60 (CCDC60) Monoclonal Antibody (Rat), APC

4-MAU807Ra21-APC
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Description: A Mouse monoclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with APC.

Coiled Coil Domain Containing Protein 60 (CCDC60) Monoclonal Antibody (Rat), Cy3

4-MAU807Ra21-Cy3
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Description: A Mouse monoclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with Cy3.

Coiled Coil Domain Containing Protein 60 (CCDC60) Monoclonal Antibody (Rat), HRP

4-MAU807Ra21-HRP
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Description: A Mouse monoclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with HRP.

Coiled Coil Domain Containing Protein 60 (CCDC60) Monoclonal Antibody (Rat), PE

4-MAU807Ra21-PE
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Description: A Mouse monoclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with PE.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Human), APC

4-PAU807Hu01-APC
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Description: A Rabbit polyclonal antibody against Human Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with APC.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Human), Cy3

4-PAU807Hu01-Cy3
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Description: A Rabbit polyclonal antibody against Human Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with Cy3.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Human), HRP

4-PAU807Hu01-HRP
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Description: A Rabbit polyclonal antibody against Human Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with HRP.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Human), PE

4-PAU807Hu01-PE
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Description: A Rabbit polyclonal antibody against Human Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with PE.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Mouse), APC

4-PAU807Mu01-APC
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Description: A Rabbit polyclonal antibody against Mouse Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with APC.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Mouse), Cy3

4-PAU807Mu01-Cy3
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Description: A Rabbit polyclonal antibody against Mouse Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with Cy3.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Mouse), HRP

4-PAU807Mu01-HRP
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Description: A Rabbit polyclonal antibody against Mouse Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with HRP.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Mouse), PE

4-PAU807Mu01-PE
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Description: A Rabbit polyclonal antibody against Mouse Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with PE.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Rat), FITC

4-PAU807Ra01-FITC
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Description: A Rabbit polyclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with FITC.

Coiled Coil Domain Containing Protein 60 (CCDC60) Monoclonal Antibody (Rat), FITC

4-MAU807Ra21-FITC
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Description: A Mouse monoclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with FITC.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Human), FITC

4-PAU807Hu01-FITC
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Description: A Rabbit polyclonal antibody against Human Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with FITC.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Mouse), FITC

4-PAU807Mu01-FITC
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Description: A Rabbit polyclonal antibody against Mouse Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with FITC.

Coiled Coil Domain Containing Protein 3 (CCDC3) Antibody

20-abx128391
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Coiled Coil Domain Containing Protein 3 (CCDC3) Antibody

20-abx171827
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Coiled Coil Domain Containing Protein 3 (CCDC3) Antibody

abx128391-100l 100 µl
EUR 287.5

Coiled Coil Domain Containing Protein 3 (CCDC3) Antibody

abx128391-1ml 1 ml
EUR 825

Coiled Coil Domain Containing Protein 3 (CCDC3) Antibody

abx128391-200l 200 µl
EUR 362.5

Coiled Coil Domain Containing Protein 3 (CCDC3) Antibody

abx171827-1ml 1 ml
EUR 875

Rat Coiled Coil Domain Containing Protein 60 (CCDC60) Protein

20-abx065994
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Rat Coiled Coil Domain Containing Protein 60 (CCDC60) Protein

abx065994-100g 100 µg
EUR 550

Rat Coiled Coil Domain Containing Protein 60 (CCDC60) Protein

abx065994-10g 10 µg
EUR 212.5

Rat Coiled Coil Domain Containing Protein 60 (CCDC60) Protein

abx065994-50g 50 µg
EUR 387.5

Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody

20-abx104220
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Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody

20-abx104221
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Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody

20-abx104222
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Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody

abx104220-100g 100 µg
EUR 750

Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody

abx104220-20g 20 µg
EUR 275

Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody

abx104220-50g 50 µg
EUR 337.5

Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody

abx104221-100g 100 µg
EUR 750

Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody

abx104221-20g 20 µg
EUR 275

Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody

abx104221-50g 50 µg
EUR 337.5

Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody

abx104222-100g 100 µg
EUR 812.5

Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody

abx104222-20g 20 µg
EUR 287.5

Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody

abx104222-50g 50 µg
EUR 362.5

Recombinant Coiled Coil Domain Containing Protein 60 (CCDC60)

RPU53470-100ug 100ug
EUR 552.2

Recombinant Coiled Coil Domain Containing Protein 60 (CCDC60)

RPU53470-1mg 1mg
EUR 2446.6

Recombinant Coiled Coil Domain Containing Protein 60 (CCDC60)

RPU53470-50ug 50ug
EUR 443.3

Recombinant Coiled Coil Domain Containing Protein 60 (CCDC60)

RPU40887-100ug 100ug
EUR 616

Recombinant Coiled Coil Domain Containing Protein 60 (CCDC60)

RPU40887-1mg 1mg
EUR 2730

Recombinant Coiled Coil Domain Containing Protein 60 (CCDC60)

RPU40887-50ug 50ug
EUR 495

Recombinant Coiled Coil Domain Containing Protein 60 (CCDC60)

RPU40888-100ug 100ug
EUR 517

Recombinant Coiled Coil Domain Containing Protein 60 (CCDC60)

RPU40888-1mg 1mg
EUR 2293.2

Recombinant Coiled Coil Domain Containing Protein 60 (CCDC60)

RPU40888-50ug 50ug
EUR 415.8

Recombinant Coiled Coil Domain Containing Protein 60 (CCDC60)

RPU807Hu01 10ug
EUR 179

Recombinant Coiled Coil Domain Containing Protein 60 (CCDC60)

4-RPU807Hu01
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Description: Recombinant Human Coiled Coil Domain Containing Protein 60 expressed in: E.coli

Recombinant Coiled Coil Domain Containing Protein 60 (CCDC60)

RPU807Mu01 10ug
EUR 200

Recombinant Coiled Coil Domain Containing Protein 60 (CCDC60)

4-RPU807Mu01
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Description: Recombinant Mouse Coiled Coil Domain Containing Protein 60 expressed in: E.coli

Recombinant Coiled Coil Domain Containing Protein 60 (CCDC60)

RPU807Ra01 10ug
EUR 168

Recombinant Coiled Coil Domain Containing Protein 60 (CCDC60)

4-RPU807Ra01
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Description: Recombinant Rat Coiled Coil Domain Containing Protein 60 expressed in: E.coli

Mouse Coiled Coil Domain Containing Protein 60 (CCDC60) Protein

20-abx065993
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Human Coiled Coil Domain Containing Protein 60 (CCDC60) Protein

20-abx166165
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Human Coiled Coil Domain Containing Protein 60 (CCDC60) Protein

abx166165-100g 100 µg
EUR 587.5

Human Coiled Coil Domain Containing Protein 60 (CCDC60) Protein

abx166165-10g 10 µg
EUR 225

Human Coiled Coil Domain Containing Protein 60 (CCDC60) Protein

abx166165-50g 50 µg
EUR 400

Mouse Coiled Coil Domain Containing Protein 60 (CCDC60) Protein

abx065993-100g 100 µg
EUR 637.5

Mouse Coiled Coil Domain Containing Protein 60 (CCDC60) Protein

abx065993-10g 10 µg
EUR 237.5

Mouse Coiled Coil Domain Containing Protein 60 (CCDC60) Protein

abx065993-50g 50 µg
EUR 437.5

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Rat), Biotinylated

4-PAU807Ra01-Biotin
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Description: A Rabbit polyclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with Biotin.

Coiled Coil Domain Containing Protein 60 (CCDC60) Monoclonal Antibody (Rat), Biotinylated

4-MAU807Ra21-Biotin
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with Biotin.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Rat), APC-Cy7

4-PAU807Ra01-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with APC-Cy7.

Coiled Coil Domain Containing Protein 60 (CCDC60) Monoclonal Antibody (Rat), APC-Cy7

4-MAU807Ra21-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rat Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with APC-Cy7.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Human), Biotinylated

4-PAU807Hu01-Biotin
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with Biotin.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Mouse), Biotinylated

4-PAU807Mu01-Biotin
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with Biotin.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Human), APC-Cy7

4-PAU807Hu01-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with APC-Cy7.

Coiled Coil Domain Containing Protein 60 (CCDC60) Polyclonal Antibody (Mouse), APC-Cy7

4-PAU807Mu01-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Coiled Coil Domain Containing Protein 60 (CCDC60). This antibody is labeled with APC-Cy7.

Coiled Coil Domain Containing Protein 3 (CCDC3) Antibody (Biotin)

20-abx274326
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Coiled Coil Domain Containing Protein 3 (CCDC3) Antibody (Biotin)

abx274326-96tests 96 tests
EUR 387.5

Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody (Biotin)

20-abx272431
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
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Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody (Biotin)

20-abx273381
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
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Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody (Biotin)

abx272431-1ml 1 ml
EUR 825

Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody (Biotin)

abx272431-200l 200 µl
EUR 362.5

Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody (Biotin)

abx273381-100mg 100 mg
EUR 900

Coiled Coil Domain Containing Protein 80 (CCDC80) Antibody (Biotin)

abx273381-20mg 20 mg
EUR 387.5

Rat Coiled coil domain containing protein 60(CCDC60) ELISA kit

E01A11357 96T
EUR 700
Description: ELISA

Rat Coiled coil domain containing protein 60(CCDC60) ELISA kit

E02C1090-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Coiled coil domain containing protein 60(CCDC60) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Coiled coil domain containing protein 60(CCDC60) ELISA kit

E02C1090-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Coiled coil domain containing protein 60(CCDC60) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Coiled coil domain containing protein 60(CCDC60) ELISA kit

E02C1090-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Coiled coil domain containing protein 60(CCDC60) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Coiled coil domain containing protein 60(CCDC60) ELISA kit

E07C1090-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Coiled coil domain containing protein 60(CCDC60) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Coiled coil domain containing protein 60(CCDC60) ELISA kit

E07C1090-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Coiled coil domain containing protein 60(CCDC60) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Coiled coil domain containing protein 60(CCDC60) ELISA kit

E07C1090-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Coiled coil domain containing protein 60(CCDC60) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Coiled coil domain containing protein 60(CCDC60) ELISA kit

E08C1090-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Coiled coil domain containing protein 60(CCDC60) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Coiled coil domain containing protein 60(CCDC60) ELISA kit

E08C1090-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Coiled coil domain containing protein 60(CCDC60) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Coiled coil domain containing protein 60(CCDC60) ELISA kit

E08C1090-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Coiled coil domain containing protein 60(CCDC60) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Coiled Coil Domain Containing Protein 60 (CCDC60) ELISA Kit

abx505419-96tests 96 tests
EUR 687.5

Goat Coiled coil domain containing protein 60(CCDC60) ELISA kit

E01A46269 96T
EUR 700
Description: ELISA

Goat Coiled coil domain containing protein 60(CCDC60) ELISA kit

E06C1090-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Coiled coil domain containing protein 60(CCDC60) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Coiled coil domain containing protein 60(CCDC60) ELISA kit

E06C1090-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Coiled coil domain containing protein 60(CCDC60) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Coiled coil domain containing protein 60(CCDC60) ELISA kit

E06C1090-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Coiled coil domain containing protein 60(CCDC60) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Coiled Coil Domain Containing Protein 80 (CCDC80) Polyclonal Antibody

CAU21626-100ul 100ul
EUR 255.4

Coiled Coil Domain Containing Protein 80 (CCDC80) Polyclonal Antibody

CAU21626-200ul 200ul
EUR 319.2

Coiled Coil Domain Containing Protein 80 (CCDC80) Polyclonal Antibody

CAU21627-100ul 100ul
EUR 235.2

Coiled Coil Domain Containing Protein 80 (CCDC80) Polyclonal Antibody

CAU21627-200ul 200ul
EUR 294

Coiled Coil Domain Containing Protein 80 (CCDC80) Polyclonal Antibody

CAU21628-100ul 100ul
EUR 235.2

Coiled Coil Domain Containing Protein 80 (CCDC80) Polyclonal Antibody

CAU21628-200ul 200ul
EUR 294
Dysregulated effector binding as a result of conformational adjustments within the swap I-interswitch-switch II module possible underlies the xm phenotype. One such effector could also be GPR89, putatively an ion channel or G protein-coupled receptor (GPCR). RABL3, however not RABL3xm, strongly related to and stabilized GPR89, and an N-ethyl-N-nitrosourea (ENU)-induced mutation (explorer) in Gpr89 phenocopied Rabl3xm.

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